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Ambien is a drug that acts on the sleep centers located in the brain and is therefore indicated for the treatment of occasional, temporary, or chronic insomnia.
How to use
The drug should be used, if possible, for a short time, not exceeding 4 weeks. An increase in the duration of treatment beyond the maximum period is carried out after a re-evaluation of the patient’s condition.
The duration of treatment for transient insomnia is from 2 to 5 days, for situational insomnia – from 2 to 3 weeks. In chronic insomnia, the duration of the course of treatment is determined by the doctor individually.
Ambien is taken orally. The recommended dose for adults is 10 mg at bedtime.
In elderly patients, patients with impaired liver function, or with chronic pulmonary insufficiency, zolpidem is prescribed at an initial dose of 5 mg and, if necessary, increased to Ambien 10 mg.
In patients with impaired renal function, it is recommended to start treatment with a dose of 2.5 mg, although the accumulation of Ambien or its metabolites in this category of patients has not been noted.
For people over 65 years of age who have liver failure or are weak, as they tend to be more sensitive to the effects of Ambien, it is recommended to take only half a tablet, equivalent to 5 mg per day.
Who should not use
Ambien should not be used by people with hypersensitivity to the active substance or any of the components of the formula. In addition, it is also contraindicated in people with severe or acute respiratory failure or liver failure.
It should also not be used in children under the age of 18 and women who are pregnant or breastfeeding.
Contraindications:
- ● syndrome of glucose-galactose malabsorption, lactose intolerance, lactase deficiency;
- ● liver failure in chronic, acute, or severe form;
- ● severe and/or acute respiratory failure;
- ● sleep apnea syndrome;
- ● severe myasthenia gravis;
- ● individual intolerance to the components of the zolpidem.
With caution, it is recommended to prescribe Ambien to patients with mild to moderate hepatic insufficiency, mental illness, depression, alcohol, drug and other types of addiction, mild to moderate respiratory failure.
Possible side effects
The most common side effects that may occur with the use of Ambien are hallucinations, agitation, nightmares, drowsiness, headache, dizziness, exacerbation of insomnia, anterograde amnesia, diarrhea, nausea, vomiting, abdominal pain, back pain, infection of the tract. lower and upper respiratory tract and fatigue.
To reduce the risk of developing rebound insomnia after long-term use of Ambien, it is recommended to discontinue the zolpidem with a gradual decrease in the daily dose.
Overdose
An overdose of Ambien can be determined by symptoms such as lowered blood pressure, depression of the respiratory center, impaired consciousness (from drowsiness to coma). Gastric lavage is recommended as a first aid measure. The specific antidote is flumazenil. Even if the patient shows signs of pronounced arousal, the use of any sedative drugs is strictly contraindicated. Hemodialysis is considered ineffective. If necessary, symptomatic therapy can be prescribed, which is carried out in a hospital setting.
Special instructions
The need for prescribing zolpidem should be determined by the doctor after establishing the cause of sleep disturbance, which may be associated with a disorder of the patient’s psyche or nervous system. The absence of a clinical effect after 7-14 days of taking Ambien 10 mg requires a correction of the treatment regimen, including additional medication prescriptions. The development of side effects from the nervous system is often individual and dose-dependent.
Therefore, to reduce their severity, it is recommended to take the drug, especially for elderly patients, already in bed or before going to bed. Ambien should not be prescribed as the main tool in the treatment of mental pathologies, depression. Ambien should be used with extreme caution in patients with depression, as it may mask the symptoms of developing depression, which increases suicidal tendencies.
In the absence of a therapeutic effect in the treatment of insomnia, the patient needs to re-conduct a mental examination for possible depression. To reduce the risk of developing anterograde amnesia, the patient must comply with the drug regimen, which requires the creation of conditions for 7-8 hours of uninterrupted sleep.

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